Glutathione plays multiple vital roles: it neutralizes free radicals, supports the immune system, protects mitochondrial function, and helps the liver process metals, chemicals, and metabolic waste. It also reduces oxidative stress, which is closely linked to chronic inflammation, neurodegeneration, and accelerated aging. In today’s world—surrounded by synthetic chemicals, pollution, and electromagnetic stressors—the body relies heavily on glutathione to cope with this constant load.

Glutathione and cancer

Cancer creates a state of extremely high oxidative stress in the body. Tumor cells generate large amounts of reactive molecules that damage surrounding tissues, and healthy cells depend on glutathione to protect themselves in this environment.

Many people undergoing cancer treatment also experience a drop in their natural glutathione levels due to inflammation, stress, infections, nutritional deficiencies, and certain medications.

Glutathione is particularly relevant because it helps protect healthy tissues during chemotherapy and radiotherapy. By strengthening the antioxidant capacity of normal cells, it may reduce common treatment-related side effects such as fatigue, nausea, inflammation, mucosal irritation, and reduced white blood cell counts.

Healthy cells regulate glutathione efficiently, whereas tumor cells often cannot. This difference allows patients to benefit from cellular protection without reinforcing tumour behaviour.

An additional key role of glutathione in cancer is immune support. Adequate glutathione levels are necessary for lymphocyte activation, natural killer (NK) cell function, and balanced inflammatory responses. A well-supported immune system is essential during treatment and throughout recovery.

How to increase glutathione naturally

The body produces glutathione continuously. The aim is to support this natural process through nutrition, lifestyle, and appropriate supplementation—especially for those seeking non-invasive approaches.

NAC (N-Acetylcysteine)

NAC is the most effective oral supplement for increasing glutathione. It provides cysteine, the amino acid needed to build glutathione, and is widely used in medical practice with strong scientific support.

Sulfur-rich foods

Cysteine is the limiting factor in glutathione synthesis, making sulfur-containing foods essential. Without sufficient cysteine, cells cannot produce enough glutathione.

• eggs
• garlic
• onions
• broccoli
• cauliflower
• kale
• Brussels sprouts
• beef and poultry

Selenium and zinc

These minerals activate glutathione-dependent enzymes. Selenium forms part of glutathione peroxidase (GPx), while zinc supports antioxidant and immune pathways. Brazil nuts, eggs, fish, red meat, and pumpkin seeds are excellent sources.

Alpha-lipoic acid

Alpha-lipoic acid helps recycle oxidised glutathione back into its active form, supporting mitochondrial function and cellular repair.

Whey protein

For those who tolerate dairy, whey protein provides bioactive cysteine and naturally supports glutathione production.

Curcumin

Curcumin activates detoxification pathways and stimulates the body’s natural antioxidant response.

Sleep and moderate exercise

Deep sleep is essential for regenerating antioxidants. Gentle, regular movement—walking, cycling, swimming, yoga—supports glutathione production without overwhelming the system.

Avoid factors that deplete glutathione

Alcohol, smoking, excessive sugar, chronic stress, environmental toxins, and lack of sleep significantly reduce glutathione levels. Minimising these factors helps preserve the body’s natural antioxidant capacity.